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Index > Protein center > Hcrtr1(Gene name) > Rat
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  • Hcrtr1 (Gene name),
  • Orexin receptor type 1 (Protein name ),  OX1R_RAT from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Hcrtr1;
    Protein name:
    Orexin receptor type 1(Ox-1-R;Ox1-R;Ox1R);
    Alternative:
    Hypocretin receptor type 1;
    Organism:
    Rat (Rattus norvegicus). 
    General Annotation
    Sub Unit:
    N/A
    Function:
    Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade.
    Subcellular Location:
    Cell membrane Multi-pass membrane protein
    Protein Attributes:
    Sequence length:
    416
    Sequence:
    50:
    MEPSATPGAQ | PGVPTSSGEP | FHLPPDYEDE | FLRYLWRDYL | YPKQYEWVLI | 
    100:
    AAYVAVFLIA | LVGNTLVCLA | VWRNHHMRTV | TNYFIVNLSL | ADVLVTAICL | 
    150:
    PASLLVDITE | SWLFGHALCK | VIPYLQAVSV | SVAVLTLSFI | ALDRWYAICH | 
    200:
    PLLFKSTARR | ARGSILGIWA | VSLAVMVPQA | AVMECSSVLP | ELANRTRLFS | 
    250:
    VCDERWADEL | YPKIYHSCFF | FVTYLAPLGL | MGMAYFQIFR | KLWGPQIPGT | 
    300:
    TSALVRNWKR | PSEQLEAQHQ | GLCTEPQPRA | RAFLAEVKQM | RARRKTAKML | 
    350:
    MVVLLVFALC | YLPISVLNVL | KRVFGMFRQA | SDREAVYACF | TFSHWLVYAN | 
    400:
    SAANPIIYNF | LSGKFREQFK | AAFSCCLPGL | GPSSSARHKS | LSLQSRCSVS | 
    416:
    KVSEHVVLTT | VTTVLS
    3D Structure:
    N/A
    Predicted Eptitope:
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    EIAab Sequence  Vaild Sequence:
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    Related Databases
    String:
    KEGG:
    UniGene:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Rat Ox-1-R
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    E0984h
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    ELISA Kit for Rat Ox-1-R
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    ELISA Kit for Rat Ox-1-R
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    E0984m
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    ELISA Kit for Rat Ox-1-R
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    E0984r
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    Packing:
    96T
    ELISA Kit for Rat Ox-1-R
    Cat.:
    E0984b
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat Ox-1-R
    Cat.:
    U0984m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Rat Ox-1-R
    Cat.:
    U0984r
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Rat Ox-1-R
    MSDS:
    Please sign in first.
    CLIA Kit for Rat Ox-1-R
    Cat.:
    U0984h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Rat Ox-1-R
    Cat.:
    U0984b
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Rat Ox-1-R
    Polyclonal Antibody for Rat Ox-1-R
    Cat.:
    P0984Rb-h
    Price:
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Ox-1-R
    Polyclonal Antibody for Rat Ox-1-R
    Cat.:
    P0984Rb-r
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Rat Ox-1-R
    Cat.:
    P0984Rb-m
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Rat Ox-1-R
    Monoclonal Antibody for Rat Ox-1-R
    Monoclonal Antibody for Rat Ox-1-R
    Monoclonal Antibody for Rat Ox-1-R
    Monoclonal Antibody for Rat Ox-1-R
    Protein for Rat Ox-1-R
    Protein for Rat Ox-1-R
    Protein for Rat Ox-1-R
    Protein for Rat Ox-1-R
    Protein for Rat Ox-1-R

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    References
    1. 1.
      "Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior."
      Sakurai T. , Amemiya A. , Ishii M. , Matsuzaki I. , Chemelli R.M. , Tanaka H. , Williams S.C. , Richardson J.A. , Kozlowski G.P. , Wilson S. , Arch J.R.S. , Buckingham R.E. , Haynes A.C. , Carr S.A. , Annan R.S. , McNulty D.E. , Liu W.-S. , Terrett J.A. , more...
      Cell92:573-585(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      tissue: Brain.
    2. 2.
      "Hypocretin/orexin, sleep and narcolepsy."
      Hungs M. , Mignot E.
      Bioessays23:397-408(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
    3. 3.
      "To eat or to sleep? Orexin in the regulation of feeding and wakefulness."
      Willie J.T. , Chemelli R.M. , Sinton C.M. , Yanagisawa M.
      Annu. Rev. Neurosci.24:429-458(2001) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: REVIEW
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