Protein name:
Orexin receptor type 1 (Ox-1-R;Ox1-R;Ox1R) ;
Alternative:
Hypocretin receptor type 1 ;
Organism:
Rat (Rattus norvegicus).
General Annotation
Function:
Moderately selective excitatory receptor for orexin-A and, with a lower affinity, for orexin-B neuropeptide. Seems to be exclusively coupled to the G(q) subclass of heteromeric G proteins, which activates the phospholipase C mediated signaling cascade.
Subcellular Location:
Cell membrane
Multi-pass membrane protein
Protein Attributes:
50:
MEPSATPGAQ | PGVPTSSGEP | FHLPPDYEDE | FLRYLWRDYL | YPKQYEWVLI |
100:
AAYVAVFLIA | LVGNTLVCLA | VWRNHHMRTV | TNYFIVNLSL | ADVLVTAICL |
150:
PASLLVDITE | SWLFGHALCK | VIPYLQAVSV | SVAVLTLSFI | ALDRWYAICH |
200:
PLLFKSTARR | ARGSILGIWA | VSLAVMVPQA | AVMECSSVLP | ELANRTRLFS |
250:
VCDERWADEL | YPKIYHSCFF | FVTYLAPLGL | MGMAYFQIFR | KLWGPQIPGT |
300:
TSALVRNWKR | PSEQLEAQHQ | GLCTEPQPRA | RAFLAEVKQM | RARRKTAKML |
350:
MVVLLVFALC | YLPISVLNVL | KRVFGMFRQA | SDREAVYACF | TFSHWLVYAN |
400:
SAANPIIYNF | LSGKFREQFK | AAFSCCLPGL | GPSSSARHKS | LSLQSRCSVS |
Vaild Sequence:
Related Databases
Uniprot:
ELISA Kit
CLIA Kit
Polyclonal Antibody
Monoclonal Antibody
Protein
FOR
Human
Pig
Mouse
Rat
Bovine
Polyclonal Antibody for Rat Ox-1-R
Polyclonal Antibody for Rat Ox-1-R
Polyclonal Antibody for Rat Ox-1-R
Polyclonal Antibody for Rat Ox-1-R
Polyclonal Antibody for Rat Ox-1-R
Monoclonal Antibody for Rat Ox-1-R
Monoclonal Antibody for Rat Ox-1-R
Monoclonal Antibody for Rat Ox-1-R
Monoclonal Antibody for Rat Ox-1-R
Monoclonal Antibody for Rat Ox-1-R
R&D Technical Data
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Precision
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Recovery
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Linearity
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References
1.
"Orexins and orexin receptors: a family of hypothalamic neuropeptides and G protein-coupled receptors that regulate feeding behavior."
Sakurai T.
,
Amemiya A.
,
Ishii M.
,
Matsuzaki I.
,
Chemelli R.M.
,
Tanaka H.
,
Williams S.C.
,
Richardson J.A.
,
Kozlowski G.P.
,
Wilson S.
,
Arch J.R.S.
,
Buckingham R.E.
,
Haynes A.C.
,
Carr S.A.
,
Annan R.S.
,
McNulty D.E.
,
Liu W.-S.
,
Terrett J.A.
,
Elshourbagy N.A.
,
Bergsma D.J.
,
Yanagisawa M.
more...
Cell92:573-585(1998)
[
PubMed ]
[
Europe PMC ]
[
Abstract ]
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Cited for : NUCLEOTIDE SEQUENCE [MRNA]
tissue :
Brain .
2.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW
3.
[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s)
Cited for : REVIEW